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Filtered Search Results
Medchemexpress LLC (R)-Propranolol hydrochloride | 13071-11-9 | 99.3% | C16H22ClNO2 | 50 MG
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(R)-Propranolol hydrochloride is the less active enantiomer of propranolol, a nonselective β-adrenergic receptor (βAR) antagonist. Propranolol exhibits high affinity for both β1AR and β2AR. The (R)-enantiomer can prevent adrenaline-induced cardiac arrhythmias in animals, though it requires a significantly higher dose compared to its (-)-enantiomer. It is suitable for research use.
- Less active enantiomer of a β-adrenoceptor antagonist.
- Nonselective antagonist with affinity for β1AR and β2AR.
- Demonstrates ability to prevent adrenaline-induced cardiac arrhythmias.
- Can reverse ouabain-induced ventricular tachycardia.
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Medchemexpress LLC Sulfalene-13C6 | 99.0% | C513C6H12N4O3S | 1 MG
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Sulfalene-13C6 is the 13C6 labeled version of Sulfalene, an antimalarial agent and long-acting sulfonamide antibacterial. Stable heavy isotopes, such as carbon-13, are incorporated into drug molecules for quantitation during drug development, potentially influencing pharmacokinetic and metabolic profiles.
- Used as a tracer
- Internal standard for quantitative analysis
- Applicable in metabolic flux analysis
- Useful for therapeutic drug monitoring
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Medchemexpress LLC Angiotensin I-13C6,15N (human, mouse, rat) TFA | 484-42-4 | 99.8% | 1303.42 (free base) | 1 MG
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Angiotensin I-13C6,15N (human, mouse, rat) TFA is a 13C and 15N labeled compound. It is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE). This product is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC CHMFL-PI4K-127 | 2377604-81-2 | C18H15ClN4O3S | 50 MG
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CHMFL-PI4K-127 is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor. It demonstrates strong antimalarial efficacy against 3D7 Plasmodium falciparum and drug-resistant strains, showing high selectivity over human kinases.
- Potent and highly selective PfPI4K inhibitor
- IC50 of 0.9 nM against PfPI4K
- Potent activity against 3D7 Plasmodium falciparum (EC50 of 25.1 nM)
- Effective against drug-resistant strains of P. falciparum (EC50 values of 23-47 nM)
- Exhibits antimalarial efficacy in both blood and liver stages in rodent models
- Oral administration of 60 mg/kg daily for 7 days showed suppressive effects in P. yoelii infected mice
- A single oral dose of 1 mg/kg provided full protection and cure in the liver stage in rodent models
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Medchemexpress LLC Butyraldehyde 2,4-dinitrophenylhydrazone-d3 | 259824-54-9 | 99.0% | 255.25 | 1 MG
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Butyraldehyde 2,4-dinitrophenylhydrazone-d3 is the deuterium labeled Butyraldehyde 2,4-dinitrophenylhydrazone. It is intended for research use only. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Propranolol glycol | 36112-95-5 | MFCD00673941 | 99.3% | 218.25 g/mol | C13H14O3 | 25 MG
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Propranolol glycol is an endogenous metabolite of propranolol used in research to study drug metabolism and anticonvulsant activity. It is supplied as a purified chemical standard for analytical, pharmacological, and in vivo studies, with associated safety and quality documentation for proper handling.
- Metabolite with reported anticonvulsant activity.
- High purity suitable for analytical and pharmacological studies.
- Supplied as a stable solid standard for in vitro and in vivo research.
- Characterized by CAS 36112-95-5 and molecular weight 218.25 g/mol.
- Includes SDS and certificate of analysis for quality verification.
- Appropriate for drug metabolism and seizure-model investigations.
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Sigma Aldrich Fine Chemicals Biosciences Isovaleraldehyde 97 fG1KG
Isovaleraldehyde is one of the flavor compounds identified in wheat corn-grits and tequila.
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Medchemexpress LLC Oxacillin-13C6 (sodium) | 1173-88-2 | 99% | 1 MG
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Oxacillin-13C6 (sodium) is the 13C6 labeled Oxacillin (sodium), a narrow-spectrum β-lactam antibiotic. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. However, MCE has not independently confirmed the accuracy of these methods.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during the drug development process
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs
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Medchemexpress LLC Pentacosane | 629-99-2 | 100 MG
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Pentacosane is a major component found in the acetone extract of Curcuma raktakanda and the essential oil from the leaves of Malus domestica. It exhibits anti-cancer activities, specifically against C-6, A549 (lung carcinoma), CHOK1 (ovarian), and THP-1 (acute monocytic leukemia) cells.
- Major component in Curcuma raktakanda extract
- Found in Malus domestica essential oil
- Exhibits anti-cancer activities
- Active against lung carcinoma cell lines
- Active against ovarian cell lines
- Active against acute monocytic leukemia cell lines
- White to off-white solid appearance
- Purity of 98.0%
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Medchemexpress LLC BODIPY 576/589 | 150173-78-7 | 96.2% | 329.11 | 5 MG
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BODIPY 576/589 is a long wavelength biological labeled dye for research use. It contains a free COOH-group and features emission (Em) at 589 nm and excitation (Ex) at 576 nm. This dye is suitable for various biological conjugation and protein labeling applications.
- Long wavelength biological labeled dye
- Contains a free COOH-group
- Emission wavelength at 589 nm
- Excitation wavelength at 576 nm
- Suitable for protein labeling protocols
- Stable under recommended storage conditions
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Selleck Chemical LLC Rhodamine 123 S3577-5mg
Rhodamine 123 (RH-123 R-22420) is a fluorescent cationic dye used to label mitochondria in living cells Rhodamine 123 inhibits ADP-stimulated respiration of mitochondria with Ki 12 M and ATPase activity of inverted inner membrane vesicles with Ki of 126 M and partially purified F1-ATPase with Ki of 177 M
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Selleck Chemical LLC S-Propranolol hydrochloride
(S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol is a -Adrenoceptor ( -Adrenergic Receptor) antagonist with log Kd values of -8 16 -9 08 and -6 93 for 1 2 and 3 respectively
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Medchemexpress LLC Anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2h,9h)-tetrone, 2,9-bis(4-ethoxyphenyl)- | 24108-89-2 | 98.01% | 10 G
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C.I. Pigment red 123 is a critical colorant used to add or alter color in various materials. It remains chemically stable and largely unaffected by the carrier or medium it is incorporated into. Its applications span multiple industries, including textile, medicine, food, cosmetics, plastics, paint, ink, photography, and paper.
- Versatile colorant: used across diverse industries for coloring purposes.
- Chemical stability: largely unaffected by the carrier or medium it is incorporated into.
- Wide application range: applicable in textile, medicine, food, cosmetics, plastics, paint, ink, photography, and paper industries.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Trans-2-hexadecenal | 22644-96-8 | 99.9% | 238.41 | 1 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(E)-2-Hexadecenal (trans-2-Hexadecenal) is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. It activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK. This product has potential applications in research related to sphingolipid signaling pathways.
- MLK3 activator
- Induces cytoskeletal remodeling
- Leads to cell rounding, detachment, and apoptosis
- Activates MLK3 signaling pathway
- Phosphorylates MKK4/7 and JNK
- Activates downstream targets of JNK
- Potential applications in sphingolipid signaling pathway research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MBP Agarose (Dextrin) 6FF | 5 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MCE MBP Agarose (Dextrin) 6FF is prepared by covalently coupling dextrin to an agarose matrix for one-step purification of fusion proteins. It features high binding capacity, excellent specificity, and superior ligand stability. Bound fusion protein can be gently eluted using 10 mM maltose, preserving biological activity. The tag can be removed by site-specific protease cleavage.
- High binding capacity
- Excellent specificity
- Superior ligand stability
- Enables one-step purification of fusion proteins
- Gentle elution preserves biological activity
- Enhances solubility of heterologous proteins
- Improves expression levels
- Promotes proper protein folding
- Tag removable by specific proteases
- Suitable for protein expression, localization, purification, and immunoassays
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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